Why the study?
Efforts to counteract African swine fever have been hampered by the lack of convenient tools to engineer African swine fever virus, largely due to its large noninfectious genome.
The development of a synthetic genomics-based reverse genetics system for ASFV will facilitate the creation of therapeutics and vaccines for African swine fever.
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Provides new ASFV engineering tool; leaves open impact on vaccines or countermeasures.
Fuchs et al. (2025) studied this question.
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