An Aetiological Evaluation of Increased Occurrence of Congenital Limb Reduction Abnormalities in Hungary, 1975–1978

In Hungary a significant increase occurred in the birth prevalence of congenital limb reduction abnormalities from 1975 to 1978 after the introduction of a new population policy in 1974. A case-control study showed a slight increased use of drugs for ovulation induction, oral contraceptives prior to conception and more frequent extramarital births as well as unwanted pregnancies.