Why the study?
Does radionuclide angiocardiography allow clear scintigraphic diagnosis in patients with congenitally corrected transposition of the great arteries?
Does radionuclide angiocardiography allow clear scintigraphic diagnosis in patients with congenitally corrected transposition of the great arteries?
Gated cardiac blood pool imaging is a useful non-invasive tool for diagnosing congenitally corrected transposition of the great arteries.
May aid noninvasive CTGA diagnosis in select cases; leaves open validation against echocardiography or MRI.
Congenitally corrected transposition of the great arteries (CTGA) may constitute a pitfall for interpretation of radionuclide angiocardiography, since the two anatomic discordances cancel each other from a physiologic point of view. However, the unusual shape of the ventricles (due to ventricular discordance) and the relative position of the great arteries (due to transposition) can allow a clear scintigraphic diagnosis, especially for CTGA with mild or absent associated congenital anomalies. Five cases are described. Gated cardiac blood pool imaging is particularly helpful since it permits multiple views, allowing a more detailed study of the scintigraphic signs.
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Brendel et al. (1984) studied this question.
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