January 1, 2003Journal of Receptors and Signal Transduction

The Expression of Urotensin II Receptor (U2R) is Up‐regulated by Interferon‐γ

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Population

human rhabdomyosarcoma cell line TE-671

Design

Preclinical

Authors

MBMagdalena BirkerIdorsia (Switzerland)CBCéline Boukhadra RSR. O. StuderIdorsia (Switzerland)

Discussion

Member takes

Implication

May implicate IFNgamma in U2R changes during heart failure inflammation; animal data leave open human relevance.

Structured PICO

Population

human rhabdomyosarcoma cell line TE-671

Intervention

Interferon gamma (IFNgamma)

Outcome

Expression of U2R mRNA and functional U-II high affinity binding sitessurrogate

IFNgamma up-regulates U2R expression, suggesting a potential mechanism for the increased U2R density observed in the heart tissue of congestive heart failure patients during inflammatory responses.

Cite This Study

Birker et al. (2003) studied this question.

synapsesocial.com/papers/6a723e0ca7fbea1e44089f97 https://doi.org/10.1081/rrs-120026972

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The Expression of Urotensin II Receptor (U2R) is Up‐regulated by Interferon‐γ

Discussion

Member takes

Implication

Structured PICO

Cite This Study

The Expression of Urotensin II Receptor (U2R) is Up‐regulated by Interferon‐γ

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider