Why the study?
Achieving optimal guideline-directed medical therapy in HFrEF is challenging, and COVID-19 created a need to explore new ways to deliver care.
Does an NP-led telehealth programme improve GDMT titration and clinical parameters in patients with HFrEF?
Does an NP-led telehealth programme improve GDMT titration and clinical parameters in patients with HFrEF?
An NP-led telehealth program for HFrEF patients facilitated rapid GDMT titration and improved clinical parameters while reducing patient travel burden.
May support NP-led telehealth for rapid GDMT titration in HFrEF; leaves open need for randomized outcome trials.
AIMS: Heart failure with reduced ejection fraction (HFrEF) is associated with poor outcomes. While several medications are beneficial, achieving optimal guideline-directed medical therapy (GDMT) is challenging. COVID-19 created a need to explore new ways to deliver care. METHODS: Fifty consecutive patients were taught to identify fluid congestion and monitor their vital signs using BP monitors and electronic scales with NP-led telephone support. Quantitative data were collected and a patient experience interview was performed. RESULTS: The majority (76%) of the cohort (male, 76%; Māori/Pacific, 58%) had a new diagnosis of HFrEF, with 90% having severe left ventricular (LV) dysfunction. There were 216 contacts (129 (60%) by telephone), which eliminated travelling, (time saved, 2.12 hours per patient), petrol costs ($58.17 per patient), traffic pollution (607 Kg of CO2) and time off work. Most (75%) received contact within two weeks and 75% were optimally titrated within two months. Improvements in systolic BP (SBP) (124mmHg to 116mmHg), pulse (78 bpm to 70 bpm) and N-terminal pro-brain natriuretic peptide (NT-proBNP) (292 to 65) were identified. Of the 43 patients who had a follow-up transthoracic echocardiogram (TTE), 33 (77%) showed important improvement in left ventricular ejection fraction (LVEF). CONCLUSIONS: Patients found the process acceptable and experienced rapid titration with less need for clinic review with titration rates comparable with most real-world reports.
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McLachlan et al. (2025) studied this question.
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