Why the study?
Does bepridil reverse electrical remodeling and L-type calcium channel downregulation in a canine model of persistent atrial tachycardia?
Does bepridil reverse electrical remodeling and L-type calcium channel downregulation in a canine model of persistent atrial tachycardia?
Bepridil partially reverses atrial electrical remodeling and prevents L-type calcium channel downregulation in a canine model of atrial tachycardia.
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Bepridil attenuated remodeling in this canine model; hypothesis-generating and should not yet change clinical practice.
Nishida et al. (2007) studied this question.
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