Why the study?
Does polytherapy with antipsychotics and antidepressants increase QTc interval compared to monotherapy in female psychiatric patients?
Population
61 hospitalized women meeting ICD-10 criteria for schizophrenia, schizoaffective psychosis, delusional…
Comparison
Polytherapy consisting of an antipsychotic agent… vs Monotherapy consisting of an antipsychotic or an…
Design
Cohort
Follow-up
two weeks
Authors
Loading...
No QTc difference with short-term polytherapy in this female cohort; leaves open longer-term arrhythmia risks and requires prospective validation.
Does polytherapy with antipsychotics and antidepressants increase QTc interval compared to monotherapy in female psychiatric patients?
Concomitant use of antipsychotics and antidepressants did not significantly prolong the QTc interval compared to monotherapy after two weeks of treatment in female psychiatric patients.
Sumić et al. (2007) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: