Why the study?
Does AT1R blocking in bone marrow cells prevent the progression of atherosclerosis?
Design
Review
Authors
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Hypothesis-generating for bone marrow AT1R blockade in atherosclerosis; prospective trials needed before clinical consideration.
Does AT1R blocking in bone marrow cells prevent the progression of atherosclerosis?
Targeting the local bone marrow renin-angiotensin system via AT1R blockade may offer a novel therapeutic strategy for preventing atherosclerosis.
Beyazıt et al. (2010) studied this question.