An Unusual Case of Flecainide‐induced QT Prolongation Leading to Cardiac Arrest

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Population

32-year-old man with a structurally normal heart and persistent atrial fibrillation

Design

Case_report

Authors

Discussion

Flecainide escalation may warrant QT monitoring; case reports leave open population-level incidence and monitoring protocols.

Population

32-year-old man with a structurally normal heart and persistent atrial fibrillation

Intervention

Flecainide dose increased to 150 mg twice/day (background therapy included diltiazem)

Outcome

QT prolongation leading to cardiac arrest (polymorphic ventricular tachycardia)safety

Flecainide can rarely induce QT prolongation leading to torsades de pointes, emphasizing the importance of periodic ECG monitoring.

Oguayo et al. (2014) studied this question.

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