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While long-term cardiac function is generally acceptable in survivors of the Norwood sequence for hypoplastic left heart syndrome, significant neurological and neuropsychological morbidity remains a major concern requiring specialized care.
We report the results of follow-up of the complete cohort of Norwegian children born in the period from 1987 through 1998 in whom there was the intention to treat surgically hypoplasia of the left heart using the Norwood sequence of operations. Of the 54 children, 21 are alive. Of these, 15 have been extensively studied, while the medical state of all the remaining survivors is known from reports from other hospitals. Of the survivors, the majority have reasonably acceptable cardiac and haemodynamic function, but significant neurological and neuropsychological morbidity is identified within the group as a whole, which requires special attention from qualified personnel of various kinds.
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Hagemo et al. (2006) studied this question.
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