Why the study?
African swine fever is one of the most severe diseases of pigs, requiring sensitive detection methods for the virus.
Population
African swine fever virus and a plasmid containing p72
Comparison
CRISPR-Cas12a system coupled with PCR or LAMP vs irrelevant background DNA or other porcine viruses
Design
In vitro diagnostic assay development and validation study
Authors
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Advances ASFV point-of-care testing; leaves open field validation before routine veterinary use.
The CRISPR-Cas12a enhanced fluorescence assay coupled with LAMP provides a highly sensitive and specific method for detecting African Swine Fever Virus.
Tao et al. (2020) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: