Why the study?
Fulminant viral myocarditis is a rare cause of cardiogenic shock with high morbidity and mortality driven by severe myocardial inflammation, leading to growing use of acute immunosuppressive therapy.
Does acute immunosuppression improve left ventricular recovery and reduce mortality in patients with fulminant viral myocarditis?
Does acute immunosuppression improve left ventricular recovery and reduce mortality in patients with fulminant viral myocarditis?
Acute immunosuppression with IVIG and/or high-dose corticosteroids in fulminant viral myocarditis is associated with rapid LVEF recovery and low mortality.
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Immunosuppression was associated with rapid LVEF recovery in this FVM series; leaves open the need for randomized trials before practice change.
Turgeon et al. (2020) studied this question.
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