Why the study?
Do mental stress, dynamic exercise, and adrenaline infusion increase platelet sensitivity to thrombin and thrombin generation in healthy volunteers?
Population
Healthy volunteers
Comparison
Mental stress, dynamic exercise, and adrenaline… vs Time control experiments
Design
Other
Follow-up
60 minutes (recovery period)
Authors
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May heighten thrombotic risk during exertion; hypothesis-generating for stress-related ACS mechanisms in patients.
Do mental stress, dynamic exercise, and adrenaline infusion increase platelet sensitivity to thrombin and thrombin generation in healthy volunteers?
Heavy exercise and adrenaline infusion reversibly increase platelet aggregability and thrombin formation, providing a potential physiological mechanism for stress-induced acute coronary syndromes.
Wallén et al. (1999) studied this question.
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