Why the study?
Does mental and physical stress alter platelet function in patients with stable angina pectoris compared to healthy controls?
Population
113 patients with stable angina pectoris (21 on aspirin) and 50 matched healthy controls
Comparison
Mental stress and physical stress/exercise vs Resting state and healthy matched controls
Design
Cross-sectional
Authors
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Mental stress may heighten platelet activation in stable angina; hypothesis-generating and should not yet change practice.
Does mental and physical stress alter platelet function in patients with stable angina pectoris compared to healthy controls?
Mental stress induces more pronounced platelet activation in patients with stable angina compared to healthy controls, whereas physical exercise activates platelets similarly in both groups and is not effectively inhibited by aspirin.
Wallén et al. (1997) studied this question.
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