Population
Voltage-dependent Ca2+ channels (in vitro model)
Comparison
Point mutations in Alpha Interaction Domain and… vs Wild-type beta 1b subunit
Design
Preclinical
Authors
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Residues may guide targeted mutagenesis studies; leaves open their relevance to human channel function or disease.
Identifies specific critical amino acid residues required for the interaction between alpha1 and beta subunits in voltage-dependent calcium channels.
Waard et al. (1996) studied this question.
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