Population
In vitro models of voltage-dependent Ca2+ channel subunits (alpha 1A and beta 4)
Design
Preclinical
Authors
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May guide isoform-specific channel modulation studies; leaves open translation to human cardiovascular disease.
Identifies a specific interaction site between the beta 4 and alpha 1A subunits of voltage-gated calcium channels, providing a molecular basis for isoform-specific functional effects.
Walker et al. (1998) studied this question.
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