Why the study?
Does ivabradine improve image quality in patients undergoing coronary CTA?
Does ivabradine improve image quality in patients undergoing coronary CTA?
Ivabradine may serve as an effective alternative to beta-blockers for lowering heart rate to improve image quality during coronary CTA.
Ivabradine may serve as beta-blocker alternative for coronary CTA heart rate control; hypothesis-generating, requires randomized confirmation.
Heart rate during coronary computed tomographic angiography (coronary CTA) has a direct correlation with image quality and detection of coronary artery disease. Beta blocking agents are the most commonly used drugs to lower the heart rate, but their use is limited due to adverse effects and contraindications. Ivabradine (IVA) is a novel drug that selectively acts on cardiac pacemaker cells and lowers heart rate. This brief review article emphasizes the importance of slow heart rate for coronary CTA image quality and pre-treatment with IVA as a negative chronotropic agent. We compared the role of other drugs used for this purpose.
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Javed et al. (2015) studied this question.
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