Why the study?
Does the dexamethasone suppression test predict treatment response to antidepressant medication in elderly individuals with major depression?
Population
44 elderly individuals with DSM-III diagnoses of major depression
Comparison
Antidepressant medication vs Suppressor response to the dexamethasone…
Design
Cohort
Authors
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DST may flag elderly patients needing higher antidepressant doses or facing poorer response; leaves open whether it should guide therapy.
Does the dexamethasone suppression test predict treatment response to antidepressant medication in elderly individuals with major depression?
The dexamethasone suppression test may help predict treatment response and medication requirements in elderly patients with major depression.
Spar et al. (1983) studied this question.
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