Why the study?
Do low plasma adiponectin levels predict the progression of coronary artery calcification in type 1 diabetic and nondiabetic subjects?
Population
306 subjects aged 19 to 59 years, comprising patients with type 1 diabetes and nondiabetic subjects.
Comparison
Plasma adiponectin levels (exposure) vs Higher vs lower plasma adiponectin levels
Design
Case-control
Follow-up
average 2.6 years (range, 1.6 to 3.3)
Authors
Loading...
Higher adiponectin levels may mark lower CAC progression risk; hypothesis-generating and requires prospective validation before clinical adoption.
Do low plasma adiponectin levels predict the progression of coronary artery calcification in type 1 diabetic and nondiabetic subjects?
Low plasma adiponectin levels independently predict the progression of coronary artery calcification in both type 1 diabetic and nondiabetic individuals.
Maahs et al. (2005) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: