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March 1, 2008The Journal of Alternative and Complementary Medicine

Stress Management Versus Lifestyle Modification on Systolic Hypertension and Medication Elimination: A Randomized Trial

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Why the study?

Does stress management (relaxation response training) reduce systolic blood pressure and facilitate medication elimination compared to lifestyle modification in older adults with isolated systolic hypertension?

Population

122 patients aged ≥55 years with isolated systolic hypertension taking at least two antihypertensive…

Comparison

8 weeks of stress management, with an additional… vs 8 weeks of lifestyle modification (control).

Design

RCT, randomized, double-blind

Follow-up

8 weeks (up to 16 weeks for eligible patients)

Authors

JDJeffery A. DusekPHPatricia L. HibberdBBBeverly Buczynski

Discussion

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Overview

Relaxation response training does not augment SBP reduction beyond lifestyle modification; extends evidence for facilitating antihypertensive deprescribing.

Structured PICO

Does stress management (relaxation response training) reduce systolic blood pressure and facilitate medication elimination compared to lifestyle modification in older adults with isolated systolic hypertension?

P
Population
122 patients aged ≥55 years with isolated systolic hypertension (SBP 140-159 mm Hg, DBP <90 mm Hg) taking at least two antihypertensive medications.
I
Intervention
8 weeks of stress management (specifically relaxation response training), with an additional 8 weeks of training and supervised medication elimination for eligible patients.
C
Comparator
8 weeks of lifestyle modification (control).
O
Outcome
Change in SBP after 8 weeks.surrogate

Stress management via relaxation response training did not reduce systolic blood pressure more than lifestyle modification, but it significantly increased the likelihood of successfully eliminating an antihypertensive medication while maintaining blood pressure control.

Cite This Study

Dusek et al. (2008) studied this question.

synapsesocial.com/papers/6a7262e426a7f98052de452ehttps://doi.org/10.1089/acm.2007.0623
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A randomized controlled trial of stress reduction in African Americans treated for hypertension for over one year2005 · 194 citations
  2. 2Relation between insufficient response to antihypertensive treatment and poor compliance with treatment: a prospective case-control study2001 · 119 citations
  3. 3One-Year Study of Felodipine or Placebo for Stage 1 Isolated Systolic Hypertension2001 · 34 citations
  4. 4The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure&lt;SUBTITLE&gt;The JNC 7 Report&lt;/SUBTITLE&gt;2003 · 25,562 citations
  5. 5Prevalence of Hypertension in the US Adult Population1995 · 2,995 citations