This case highlights the risk of severe rhabdomyolysis and renal failure when statins are continued during major surgery involving extensive muscle trauma, suggesting they should be discontinued 4-7 days preoperatively.
No takes yet. Share an insight, caveat, or question.
Hypothesis-generating for statin-associated rhabdomyolysis in major surgery; prospective trials needed before changing perioperative management.
Rosenberg et al. (1995) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: