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July 27, 2007Stroke

Habitual Physical Activity and Vascular Aging in a Young to Middle-Age Population at Low Cardiovascular Risk

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Why the study?

Does habitual physical activity improve carotid artery wall thickness and stiffness in a young to middle-age population at low cardiovascular risk?

Population

432 healthy subjects free of carotid atherosclerosis and with low coronary heart disease risk as determined…

Design

Cross-sectional

Authors

MKM. KozàkovàUniversity of PisaCPCarlo PalomboGeneral CardiologyLMLeila MhamdiDanone (France)

Discussion

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Implication

Supports activity to potentially slow carotid stiffening; leaves open causal effects on stiffness or outcomes in low-risk adults.

Structured PICO

Does habitual physical activity improve carotid artery wall thickness and stiffness in a young to middle-age population at low cardiovascular risk?

P
Population
432 healthy subjects (166 men; mean age 43+/-8 years; range 30 to 60 years) free of carotid atherosclerosis and with low coronary heart disease risk as determined by the Framingham prediction score
I
Intervention
Habitual physical activity assessed objectively by actigraph (accelerometer)
O
Outcome
Carotid artery wall thickness (intima-media thickness) and stiffness (systodiastolic changes in luminal diameter) measured by B-mode ultrasonographysurrogate

Habitual physical activity is independently and inversely associated with age-related increases in carotid wall stiffness in healthy, low-risk adults.

Cite This Study

Kozàkovà et al. (2007) studied this question.

synapsesocial.com/papers/6a7264656c240de38cdc6078https://doi.org/10.1161/strokeaha.107.484949

Topics

Women and heart disease
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Regular aerobic exercise and the age-related increase in carotid artery intima-media thickness in healthy men2002 · 153 citations
  2. 2Arterial distensibility and physical activity in the ARIC study2001 · 40 citations
  3. 3Effects of age and aerobic capacity on arterial stiffness in healthy adults.1993 · 1,085 citations
  4. 4Longitudinal Changes in &OV0312;O2max: Associations with Carotid IMT and Arterial Stiffness2003 · 93 citations
  5. 5Structural, Functional, and Hemodynamic Changes of the Common Carotid Artery With Age in Male Subjects1999 · 143 citations