Why the study?
Does sudden airway occlusion produce different inspiratory muscle reflex responses in people with COPD compared to healthy age-matched controls?
Does sudden airway occlusion produce different inspiratory muscle reflex responses in people with COPD compared to healthy age-matched controls?
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The short-latency inhibitory reflex of inspiratory muscles to airway occlusion is more prevalent in COPD patients than in healthy age-matched controls, likely due to increased neural respiratory drive.
A potent short-latency reflex inhibition of inspiratory muscles produced by airway occlusion was tested in people with COPD and age-matched controls. The reflex was more prevalent in COPD, presumably due to an increased neural drive to breathe. When present, the reflex was similar in duration in the two groups, longer than historical data for younger control groups. The work reveals novel differences in reflex control of inspiratory muscles due to aging as well as COPD.
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Epiu et al. (2021) studied this question.
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