Key result
Complete pulmonary denervation via bilateral lung transplantation did not significantly alter the short-latency reflex inhibition of inspiratory muscles produced by airway occlusion compared to controls.
Why the study?
Are pulmonary afferents necessary for the reflex inhibition of human inspiratory muscles produced by airway occlusion?
Observational (n=10)
Are pulmonary afferents necessary for the reflex inhibition of human inspiratory muscles produced by airway occlusion?
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Short-latency reflex inhibition of inspiratory muscles following airway occlusion is preserved after bilateral lung transplantation, indicating it is not critically dependent on intrapulmonary receptors.
Butler et al. (1997) conducted an observational in Complete pulmonary denervation (n=10). Complete pulmonary denervation (bilateral lung transplantation) vs. Matched control subjects was evaluated on Short-latency reduction in electromyographic activity (EMG) of inspiratory muscles following brief airway occlusion. Complete pulmonary denervation via bilateral lung transplantation did not significantly alter the short-latency reflex inhibition of inspiratory muscles produced by airway occlusion compared to controls.
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