Heart failure disrupts the normal transmural gradient of NCX expression by selectively upregulating it in mid-myocardial and endocardial layers, potentially increasing vulnerability to arrhythmias.
Authors
No takes yet. Share an insight, caveat, or question.
May heighten arrhythmia risk in HF; hypothesis-generating for human validation.
Xiong et al. (2005) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: