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October 7, 2010European Heart JournalOpen Access

Heart failure reversal by ventricular unloading in patients with chronic cardiomyopathy: criteria for weaning from ventricular assist devices

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Population

47 patients with chronic cardiomyopathy as the underlying cause for heart failure, who were part of a total…

Design

Cohort

Follow-up

5 years

Authors

MDMichael DandelYWY WengHSH. Siniawski

Discussion

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Overview

These thresholds may aid VAD explant decisions; extends recovery prediction data but remains hypothesis-generating pending prospective validation.

Structured PICO

P
Population
47 patients with chronic cardiomyopathy (CCM) as the underlying cause for heart failure, who were part of a total of 90 patients weaned from bridge-to-transplant-designed ventricular assist devices (VADs) since 1995.
I
Intervention
Ventricular assist device (VAD) removal/weaning based on pre-explantation off-pump echocardiographic parameters.
O
Outcome
Post-weaning 5-year freedom from heart failure recurrence and cardiac stability lasting ≥5 years after VAD removal.hard clinical

Pre-explantation echocardiographic parameters, particularly off-pump LVEF ≥45-50%, can reliably predict long-term cardiac stability and freedom from heart failure recurrence after VAD removal in patients with chronic cardiomyopathy.

Cite This Study

Dandel et al. (2010) studied this question.

synapsesocial.com/papers/6a726df75d37378ac1df357fhttps://doi.org/10.1093/eurheartj/ehq353
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