Concentric right ventricular hypertrophy can cause biventricular diastolic pressure elevation, highlighting the physiological importance of ventricular interdependence.
RV hypertrophy may inform biventricular filling pressure assessment; extends interdependence observations but leaves causal and clinical impact open.
Patients with mild pulmonary stenosis, predominant mitral stenosis, or aortic valvular disease were studied by standard catheterization technics to determine the effect of their lesions upon both the ipsilateral and contralateral ventricles. The study suggested (1) that left heart lesions which produce an elevation of left ventricular end-diastolic pressure (LVEDP) do not necessarily cause an abnormal rise in diastolic pressure in the contralateral ventricle, (2) that eccentric right ventricular hypertrophy by definition without septal involvement may produce elevated right ventricular end-diastolic pressure without affecting LVEDP, and (3) that concentric right ventricular hypertrophy appears to effect an elevation in end-diastolic pressure in both the ipsilateral and contralateral ventricles. Possible mechanisms related to the biventricular architecture are discussed.
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Herbert et al. (1969) studied this question.
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