Why the study?
Does combined myocardial revascularisation reduce the incidence of ICD therapy or improve survival in CAD patients with VT/VF undergoing ICD implantation?
Does combined myocardial revascularisation reduce the incidence of ICD therapy or improve survival in CAD patients with VT/VF undergoing ICD implantation?
Myocardial revascularisation at the time of ICD implantation in CAD patients with VT/VF does not significantly reduce the incidence of subsequent ICD therapies or improve long-term survival compared to ICD implantation alone.
Revascularisation at ICD implantation was not associated with fewer therapies or better survival; leaves open whether it benefits CAD patients with VT/VF.
BACKGROUND: Our aim was to evaluate the occurrence of implanted cardioverter-defibrillator (ICD) shock and antitachycardia pacing (ATP), the effect of ICD therapies on mortality and the impact of revascularisation strategies on arrhythmic events. PATIENTS AND METHODS: We investigated 130 CAD patients undergoing ICD implantation between 1984 and 1999. RESULTS: Freedom of shock was 66 +/- 7 %, 48 +/- 9 % and 48 +/- 9 % after 1, 3 and 5 years in patients with revascularisation and 62 +/- 8 %, 43 +/- 8 % and 23 +/- 11 % in patients without revascularisation, respectively; p = n. s. Freedom from ATP was similar in both groups - in patients with revascularisation, 64 +/- 6 %, 58 +/- 7 % and 58 +/- 7 % and without revascularisation 56 +/- 8 %, 51 +/- 9 % and 38 +/- 10 %, respectively; p = n. s. There were no significant differences in cumulative survival between patients with and without revascularisation; p = n. s. CONCLUSIONS: CAD patients with VT/VF and with implanted ICD have, despite successful revascularisation, the same rate of device therapy and mortality as patients without an indication of revascularisation. This implies that patients with chronic ischemic heart disease and ventricular tachyarrhythmias continue to be at risk of sudden death after CABG/PTCA; evaluation for ICD implantation is warranted.
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Brockes et al. (2002) studied this question.
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