Why the study?
Coxsackievirus A24 variant is a major cause of acute hemorrhagic conjunctivitis, but assays to support studies on its genomic epidemiology and evolution across Africa were needed.
A simple tiled-amplicon-based whole genome sequencing protocol was successfully developed for CA24v to support future genomic epidemiology studies.
Enables CA24v genomic surveillance; leaves open prospective validation before clinical or public health adoption.
We developed a whole genome sequencing assay for coxsackievirus A24 variant (CA24v), a major cause of acute hemorrhagic conjunctivitis, and used it to recover three near complete genomes from the 2024 CA24v outbreak in Kenya. This assay will support studies on CA24v genomic epidemiology and evolution across Africa.
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Morobe et al. (2025) studied this question.
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