Why the study?
Does the combination of dipyridamole and aspirin inhibit whole blood platelet aggregation and ATP release in vitro?
Does the combination of dipyridamole and aspirin inhibit whole blood platelet aggregation and ATP release in vitro?
The combination of dipyridamole and aspirin inhibits both platelet aggregation and ATP release in vitro, providing a mechanistic basis for their additive effect in stroke prevention.
In vitro additive inhibition supports mechanistic rationale; hypothesis-generating only and should not change practice.
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智実 et al. (2000) studied this question.
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