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October 19, 2009Proceedings of the National Academy of SciencesOpen Access

Adenoviral transfer of HIF-1α enhances vascular responses to critical limb ischemia in diabetic mice

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KSKakali SarkarNational Institutes of HealthKFKaren Fox-TalbotJohns Hopkins UniversityCSCharles SteenbergenCross-Cutting Cardiology

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Sarkar et al. (2009) studied this question.

synapsesocial.com/papers/6a72728f8031ec7bb1dd5e4chttps://doi.org/10.1073/pnas.0910561106
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Impaired collateral vessel development in diabetes: potential cellular mechanisms and therapeutic implications2001 · 318 citations
  2. 2Critical Limb Ischemia: Definition and Natural History2004 · 151 citations
  3. 3Sustained expression of Hif‐1α in the diabetic environment promotes angiogenesis and cutaneous wound repair2007 · 178 citations