Why the study?
Do desflurane and sevoflurane reduce postinfarction ventricular dysrhythmias compared to halothane in a dog model?
Population
16 adult mongrel dogs with acute myocardial infarction and severe ventricular tachydysrhythmias induced by…
Comparison
Desflurane followed by sevoflurane at 1.5 MAC. vs Halothane (1.3%) at 1.5 MAC (n=6).
Design
Preclinical
Follow-up
9 minutes of recording after 20 minutes of equilibration…
Authors
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Animal data on volatile anesthetics for postinfarction ectopy leave open translation to human perioperative arrhythmia management.
Do desflurane and sevoflurane reduce postinfarction ventricular dysrhythmias compared to halothane in a dog model?
Desflurane and sevoflurane inhibit spontaneous postinfarction ventricular dysrhythmias in a canine model, though less effectively than halothane.
Novalija et al. (1998) studied this question.
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