What question did this study set out to answer?

May 1, 2002AnesthesiologyOpen Access

Frequency of Myocardial Infarction, Pulmonary Embolism, Deep Venous Thrombosis, and Death following Primary Hip or Knee Arthroplasty

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Why the study?

What is the frequency of myocardial infarction, pulmonary embolism, deep venous thrombosis, and death within 30 days after elective primary hip or knee arthroplasty?

Population

10,244 consecutive patients undergoing elective primary total hip or knee arthroplasty at a single…

Design

Cohort

Follow-up

30 days

Authors

MWMargaret WoodMayo Clinic CMCarlos B. MantillaWinnMed THTerese T. HorlockerNorthwestern University

Discussion

Member takes

Implication

Contemporary rates inform perioperative counseling in arthroplasty; leaves open optimized prophylaxis trials.

Key Points

To determine the 30-day frequency of clinically relevant myocardial infarction, pulmonary embolism, deep venous thrombosis, and death following elective primary hip or knee arthroplasty under contemporary perioperative management.
Reviewed medical records of consecutive patients who underwent elective primary total hip or knee arthroplasty at a single institution over a 10-year period (N=10,244).
Identified adverse events within 30 days post-surgery using prospectively collected databases with standardized diagnostic-certainty categories and validation criteria.
A total of 224 patients experienced at least one adverse event (overall rate: 2.2%), comprising deep venous thrombosis in 1.5%, pulmonary embolism in 0.7%, death in 0.5%, and myocardial infarction in 0.4%.
Adverse outcomes increased with age, notably in patients aged 70 years or older; myocardial infarction occurred more frequently in males, and pulmonary embolism was highest among patients receiving bilateral knee procedures.

Structured PICO

What is the frequency of myocardial infarction, pulmonary embolism, deep venous thrombosis, and death within 30 days after elective primary hip or knee arthroplasty?

Population

10,244 consecutive patients undergoing elective primary total hip or knee arthroplasty at a single institution over a 10-year period

Intervention

Elective primary total hip or knee arthroplasty treated according to contemporary perioperative management

Outcome

Frequency of clinically relevant myocardial infarction, pulmonary embolism, deep venous thrombosis, and death within 30 dayshard clinical

The 30-day risk of serious cardiovascular and thromboembolic complications following primary hip or knee arthroplasty in contemporary practice is approximately 2.2%.

Cite This Study

Wood et al. (2002) studied this question.

synapsesocial.com/papers/6a7278f9a528af2d65c46ec3 https://doi.org/10.1097/00000542-200205000-00017

Topics

Pulmonary embolism

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Frequency of Myocardial Infarction, Pulmonary Embolism, Deep Venous Thrombosis, and Death following Primary Hip or Knee Arthroplasty

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Frequency of Myocardial Infarction, Pulmonary Embolism, Deep Venous Thrombosis, and Death following Primary Hip or Knee Arthroplasty

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Topics

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