Uncommon Cardiac Myxoma Arising from the Right Ventricle—Imaging Insights

A 64-year-old woman (n=1) presenting with a 5-month history of progressive dyspnea and ambient air oxygen desaturation to 86%, found to have a large (30 × 60 mm) right ventricular (RV) myxoma implanted at the RV apex and prolapsing into the tricuspid valve, with a medical history of hypertension and left breast adenocarcinoma in remission (treated in 2007), evaluated in Lyon, France.

Multimodal diagnostic imaging (transthoracic echocardiography, contrast-enhanced thoracic CT with 3D volumetric reconstruction, cardiac magnetic resonance imaging, and FDG-PET-CT) followed by surgical resection of the right ventricular myxoma via right longitudinal atriotomy and RV eversion under extracorporeal circulatory assistance, biological prosthetic tricuspid valve replacement, leadless pacemaker implantation, heart failure medical therapy, and cardiac rehabilitation.

Symptom resolution and absence of tumor recurrence on transthoracic echocardiography at 3 and 9 months postoperatively