Why the study?
Does widespread vaccination with conjugate Haemophilus influenzae type b vaccines reduce oropharyngeal carriage of Hib in children aged 2 to 5 years?
Population
584 children aged 2 to 5 years old in metropolitan Atlanta
Comparison
Widespread vaccination with conjugate… vs Historical estimates from prior studies of…
Design
Cross-sectional
Authors
Loading...
Supports conjugate Hib vaccination reducing carriage; leaves open confirmation of impact on invasive disease.
Does widespread vaccination with conjugate Haemophilus influenzae type b vaccines reduce oropharyngeal carriage of Hib in children aged 2 to 5 years?
Widespread use of conjugate Hib vaccines is associated with a very low rate of Hib oropharyngeal carriage (0.17%) in children, likely contributing to the decline in invasive Hib disease.
Mohle‐Boetani et al. (1993) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: