Key result
While Hib conjugate vaccines have dramatically reduced invasive disease, persistent oropharyngeal carriage and changes in vaccine formulations can lead to disease re-emergence in high-risk populations.
Population
Children <5 years of age, including Alaskan Native, Navajo, Apache, and general US populations
Design
Editorial
Authors
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This editorial highlights that while Hib conjugate vaccines have drastically reduced disease incidence, eliminating the disease remains challenging, particularly in high-risk populations requiring early protection after the first vaccine dose.
This editorial highlights that while Hib conjugate vaccines have drastically reduced disease incidence, eliminating the disease remains challenging, particularly in high-risk populations requiring early protection after the first vaccine dose.
Mathuram Santosham (2000) conducted an editorial in Haemophilus influenzae type b (Hib) disease. Hib conjugate vaccines was evaluated. While Hib conjugate vaccines have dramatically reduced invasive disease, persistent oropharyngeal carriage and changes in vaccine formulations can lead to disease re-emergence in high-risk populations.
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