Why the study?
Does the tortuosity of white matter medullary arterioles correlate with the severity of hypertension?
Population
47 autopsied brains with age-adjusted stages of hypertension (graded according to WHO classification)
Design
Cross-sectional
Authors
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Arteriolar tortuosity may mark hypertensive small vessel disease; hypothesis-generating and requires prospective validation.
Does the tortuosity of white matter medullary arterioles correlate with the severity of hypertension?
Arteriolar tortuosity in the hemispheric white matter correlates with hypertension severity and may serve as an indicator of hypertensive small vessel disease of the brain.
Hiroki et al. (2002) studied this question.
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