Why the study?
Does preload reduction by haemodialysis affect echocardiographic indices of diastolic function in patients with chronic renal failure?
Population
17 patients with chronic renal failure in sinus rhythm with normal left ventricular systolic function
Comparison
Preload reduction by haemodialysis vs Pre-haemodialysis baseline
Design
Cohort
Follow-up
30 min following haemodialysis
Authors
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Mitral annular e' may reliably grade diastolic function despite preload shifts; supports its preference over Vp but leaves confirmation to prospective studies.
Does preload reduction by haemodialysis affect echocardiographic indices of diastolic function in patients with chronic renal failure?
Assessment of diastolic function by mitral annular early diastolic velocity appears to be preload-independent, whereas propagation velocity of early diastolic filling (Vp) is affected by preload.
Graham et al. (2003) studied this question.