Why the study?
Does female gender affect hemorheological parameters and in vitro platelet aggregation in vascular patients treated with antiplatelet agents compared to male gender?
Population
4,045 vascular patients treated with antiplatelet agents
Comparison
Female gender vs Male gender
Design
Cross-sectional
Authors
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May indicate reduced aspirin efficacy in women; hypothesis-generating for gender-specific antiplatelet trials in vascular disease.
Does female gender affect hemorheological parameters and in vitro platelet aggregation in vascular patients treated with antiplatelet agents compared to male gender?
Women treated with aspirin monotherapy exhibit higher ADP-induced platelet aggregation and fibrinogen concentrations than men, suggesting they may derive greater benefit from dual antiplatelet therapy.
Koltai et al. (2014) studied this question.
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