Population
Porcine aortic and pulmonary heart valve interstitial cells (AVICs and PVICs)
Comparison
Seeding on collagen gels and treatment with… vs Dermal fibroblasts and direct comparison between…
Design
Preclinical
Follow-up
48 hours
Authors
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These mechanobiological differences may guide valve-specific scaffolds; leaves open human translation.
Significant mechanobiological differences exist between aortic and pulmonary valve interstitial cells, with aortic cells demonstrating greater stiffness and extracellular matrix contraction potential.
Merryman et al. (2007) studied this question.
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