Population
Children with genetic disorders causing severe hypertension (Mendelian forms of hypertension)
Design
Review
Authors
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Offers mechanistic insights into renal sodium handling; hypothesis-generating for targeted therapies in primary hypertension, without changing practice.
Understanding monogenic forms of hypertension in children provides critical insights into renal sodium transport mechanisms and potential future treatment targets for primary hypertension.
R. Scott Williams (2007) studied this question.
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