Why the study?
Does the G allele of rs5068 within the NPPA locus reduce incident type 2 diabetes in individuals without known diabetes?
Does the G allele of rs5068 within the NPPA locus reduce incident type 2 diabetes in individuals without known diabetes?
The presence of the G allele of rs5068 in the NPPA locus is associated with a reduced risk of incident type 2 diabetes, suggesting a potential protective role of the atrial natriuretic peptide system in diabetes development.
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rs5068 G allele was associated with lower incident diabetes; leaves open whether NPPA variants causally influence type 2 diabetes risk.
Jujić et al. (2014) studied this question.
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