Why the study?
Do baseline plasma levels of MR-ANP and N-BNP predict new-onset diabetes and long-term glucose progression in nondiabetic individuals?
Do baseline plasma levels of MR-ANP and N-BNP predict new-onset diabetes and long-term glucose progression in nondiabetic individuals?
Low plasma levels of MR-ANP, but not N-BNP, independently predict the development of future diabetes and glucose progression over a 16-year follow-up.
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May aid diabetes risk stratification; hypothesis-generating and requires prospective validation before clinical adoption.
Magnusson et al. (2011) studied this question.
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