Why the study?
Optimal monitoring strategies and heparin dosing during ECMO support remain unclear, and evidence is lacking to guide recommendations.
Population
Children and adults supported with extracorporeal membrane oxygenation (ECMO)
Design
Review
Authors
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ECMO anticoagulation lacks evidence-based standards with high practice variability; leaves open optimal protocols pending multicenter RCTs.
Current evidence for optimal anticoagulation monitoring during ECMO is limited and relies on observational data, highlighting the urgent need for large, prospective, randomized multicenter trials.
Koster et al. (2019) studied this question.
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