Why the study?
Are there detectable reductions in cerebral blood flow and increases in cerebrovascular resistance in patients with mild cognitive impairment compared to normal controls?
Are there detectable reductions in cerebral blood flow and increases in cerebrovascular resistance in patients with mild cognitive impairment compared to normal controls?
Patients with mild cognitive impairment exhibit reduced cerebral blood flow and increased cerebrovascular resistance detectable by Doppler ultrasonography, suggesting the presence of vascular abnormalities at the pre-dementia stage.
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May indicate early cerebrovascular dysfunction in MCI; extends cross-sectional data but leaves open causality and clinical utility.
Zhang et al. (2012) studied this question.
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