Why the study?
Does oral anticoagulation at discharge improve clinical outcomes in patients with atrial fibrillation and high bleeding risk undergoing percutaneous coronary intervention with stenting?
Population
590 consecutive patients with atrial fibrillation undergoing percutaneous coronary intervention/stenting and…
Comparison
Oral anticoagulation (OAC) at discharge vs No oral anticoagulation at discharge
Design
Cohort
Follow-up
1 year
Authors
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May support OAC consideration in high HAS-BLED AF-PCI despite bleeding risk; leaves open randomized confirmation of net benefit.
Does oral anticoagulation at discharge improve clinical outcomes in patients with atrial fibrillation and high bleeding risk undergoing percutaneous coronary intervention with stenting?
In patients with atrial fibrillation undergoing PCI, oral anticoagulation improves prognosis by reducing mortality and major adverse cardiac events even in those with a high HAS-BLED bleeding risk score, despite an expected increase in major bleeding.
Ruiz-Nodar et al. (2012) studied this question.
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