Evaluates low-dose tolvaptan for early perioperative fluid balance after cardiovascular surgery, highlighting preserved urine output without worsening renal function.
Background: Perioperative management of body fluid levels after cardiovascular surgery with cardiopulmonary bypass is essential. Fluid management using tolvaptan with conventional diuretics is effective in maintaining urine output without worsening renal function. This study aimed to improve the in-out balance in the early perioperative phase using low-dose tolvaptan (3.75 mg/day).
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Matsuda et al. (2022) studied this question.
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