Why the study?
Does varying carotid sinus pressure alter the aortic flow-mean right atrial pressure relationship in anesthetized dogs?
Population
Closed-chest, naturally breathing, and anesthetized dogs
Comparison
Varying isolated carotid sinus pressure from 75… vs Different levels of isolated carotid sinus…
Design
Preclinical
Authors
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Carotid sinus pressure modulates aortic flow via vagal reflexes in dogs; leaves open translation to human baroreflex-cardiac interactions.
Does varying carotid sinus pressure alter the aortic flow-mean right atrial pressure relationship in anesthetized dogs?
The carotid sinus reflex significantly alters the flow-generating ability of the heart-lung compartment by up to 40%, but this is clearly observable only when reflex changes in aortic pressure are prevented.
KOSTIUK et al. (1976) studied this question.
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