Population
2 individuals with rheumatoid arthritis who were heterozygous for DR1 and DRw10 class II major…
Authors
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DR1 substitutions in two RA cases merit sequencing in larger cohorts; leaves open their role in shared epitope susceptibility.
The study identifies specific amino acid substitutions in the DR1 beta 1 chains of two patients with rheumatoid arthritis, suggesting conformational equivalence in the third diversity regions with the DR4 haplotype.
Merryman et al. (1989) studied this question.
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