Why the study?
Does adenovirus-mediated human adrenomedullin gene delivery reduce blood pressure and protect against cardiorenal lesions in hypertensive Dahl salt-sensitive rats?
Does adenovirus-mediated human adrenomedullin gene delivery reduce blood pressure and protect against cardiorenal lesions in hypertensive Dahl salt-sensitive rats?
Adenovirus-mediated human adrenomedullin gene delivery protects against salt-induced hypertension and cardiorenal lesions in a rat model.
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Hypothesis-generating for adrenomedullin gene therapy in salt-sensitive hypertension; human trials needed before clinical translation.
Zhang et al. (2000) studied this question.
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